All tests · Therapeutic Drug Levels · Digoxin Level

Above the range

What causes a high Digoxin Level?

Normal range 0.8-2 ng/mL (1-2.6 nmol/L SI). Specimen: Serum (trough, ≥ 6 h post-dose). See the full Digoxin Level reference page for critical values and nursing considerations.

Above the range

Common causes of a high Digoxin Level

  • Renal impairment
  • Hypokalemia (potentiates toxicity)
  • Drug interactions (amiodarone, verapamil)
  • Overdose

Looking for the other direction? See what causes a low Digoxin Level.

What is the normal range for Digoxin Level?

The standard teaching reference range for Digoxin Level is 0.8-2 ng/mL in conventional units, or 1-2.6 nmol/L in SI units. This value is measured in serum (trough, ≥ 6 h post-dose).

Digoxin Level reference range and specimen details
SpecimenSerum (trough, ≥ 6 h post-dose)
Conventional range0.8-2 ng/mL
SI range1-2.6 nmol/L
Critical value> 2.0 ng/mL is toxic (many target 0.5-0.9 in heart failure)
PanelTherapeutic Drug Levels

Full details, including nursing considerations, on the Digoxin Level normal range page. Reference ranges vary by laboratory, method, age, sex, and population - always use the range printed on the actual result.

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