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Therapeutic Drug Levels

Theophylline Level

Normal range 10-20 µg/mL (56-111 µmol/L SI). Specimen: Serum.

Also known as: aminophylline level.

10-20 µg/mLToxicity threshold: read below

Reference range

Conventionalµg/mL
1020
SIµmol/L
56111

Combined adult band. LabVals does not publish separate men's, women's, or pediatric ranges for Theophylline Level; those can be narrower than the band shown.

Theophylline Level reference range, specimen, and conversion details
SpecimenSerum
Conventional range10-20 µg/mL
SI range56-111 µmol/L
Conversion factor×5.55 (conventional → SI)
Toxicity threshold> 20 µg/mL (nausea, tachycardia, seizures)
PanelTherapeutic Drug Levels

Convert any Theophylline Level result between units on the unit converter.

What is the normal range for Theophylline Level?

The standard teaching reference range for Theophylline Level is 10-20 µg/mL in conventional units, or 56-111 µmol/L in SI units. This value is measured in serum.

What toxicity threshold is taught for Theophylline Level?

For Theophylline Level, the commonly taught toxicity threshold is: > 20 µg/mL (nausea, tachycardia, seizures).

Source: Adult reference values compiled from Pagana & Pagana, Mosby's Diagnostic and Laboratory Test Reference, and Fischbach & Dunning, A Manual of Laboratory and Diagnostic Tests. Reference ranges vary by laboratory, method, age, sex, and population - always use the range printed on the actual result.

At the bedside

Nursing considerations

  • Watch for tachyarrhythmias, nausea, and seizures as levels rise; narrow therapeutic window.
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