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Therapeutic Drug Levels

Digoxin Level

Normal range 0.8-2 ng/mL (1-2.6 nmol/L SI). Specimen: Serum (trough, ≥ 6 h post-dose).

Also known as: Lanoxin level.

0.8-2 ng/mLToxicity threshold: read below

Reference range

Conventionalng/mL
0.82
SInmol/L
12.6

Combined adult band. LabVals does not publish separate men's, women's, or pediatric ranges for Digoxin Level; those can be narrower than the band shown.

Digoxin Level reference range, specimen, and conversion details
SpecimenSerum (trough, ≥ 6 h post-dose)
Conventional range0.8-2 ng/mL
SI range1-2.6 nmol/L
Conversion factor×1.281 (conventional → SI)
Toxicity threshold> 2.0 ng/mL is toxic (many target 0.5-0.9 in heart failure)
PanelTherapeutic Drug Levels

Convert any Digoxin Level result between units on the unit converter.

What is the normal range for Digoxin Level?

The standard teaching reference range for Digoxin Level is 0.8-2 ng/mL in conventional units, or 1-2.6 nmol/L in SI units. This value is measured in serum (trough, ≥ 6 h post-dose).

What toxicity threshold is taught for Digoxin Level?

For Digoxin Level, the commonly taught toxicity threshold is: > 2.0 ng/mL is toxic (many target 0.5-0.9 in heart failure).

Source: Adult reference values compiled from Pagana & Pagana, Mosby's Diagnostic and Laboratory Test Reference, and Fischbach & Dunning, A Manual of Laboratory and Diagnostic Tests. Reference ranges vary by laboratory, method, age, sex, and population - always use the range printed on the actual result.

At the bedside

Nursing considerations

  • Hold the dose and check for nausea, visual halos, and bradycardia when toxic.
  • Hypokalemia and hypomagnesemia worsen digoxin toxicity - monitor electrolytes.
  • Digoxin immune Fab is the antidote for severe toxicity.
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