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What causes a low Bicarbonate (CO₂ content)?

Normal range 22-29 mEq/L (22-29 mmol/L SI). Specimen: Serum or plasma. See the full Bicarbonate (CO₂ content) reference page for critical values and nursing considerations.

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Common causes of a low Bicarbonate (CO₂ content)

  • Metabolic acidosis (DKA, lactic acidosis)
  • Diarrhea
  • Renal failure
  • Compensation for respiratory alkalosis

Looking for the other direction? See what causes a high Bicarbonate (CO₂ content).

What is the normal range for Bicarbonate (CO₂ content)?

The standard teaching reference range for Bicarbonate (CO₂ content) is 22-29 mEq/L in conventional units, or 22-29 mmol/L in SI units. This value is measured in serum or plasma.

Bicarbonate (CO₂ content) reference range and specimen details
SpecimenSerum or plasma
Conventional range22-29 mEq/L
SI range22-29 mmol/L
Critical value< 15 or > 40 mmol/L
PanelElectrolytes & Minerals

Full details, including nursing considerations, on the Bicarbonate (CO₂ content) normal range page. Reference ranges vary by laboratory, method, age, sex, and population - always use the range printed on the actual result.

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