All tests · Inflammatory & Other Chemistry · Osmolality, Serum

Above the range

What causes a high Osmolality, Serum?

Normal range 275-295 mOsm/kg (275-295 mmol/kg SI). Specimen: Serum. See the full Osmolality, Serum reference page for critical values and nursing considerations.

Above the range

Common causes of a high Osmolality, Serum

  • Dehydration
  • Hypernatremia
  • Hyperglycemia
  • Toxic alcohol ingestion (osmolar gap)

Looking for the other direction? See what causes a low Osmolality, Serum.

What is the normal range for Osmolality, Serum?

The standard teaching reference range for Osmolality, Serum is 275-295 mOsm/kg in conventional units, or 275-295 mmol/kg in SI units. This value is measured in serum.

Osmolality, Serum reference range and specimen details
SpecimenSerum
Conventional range275-295 mOsm/kg
SI range275-295 mmol/kg
Critical value< 265 or > 320 mOsm/kg
PanelInflammatory & Other Chemistry

Full details, including nursing considerations, on the Osmolality, Serum normal range page. Reference ranges vary by laboratory, method, age, sex, and population - always use the range printed on the actual result.

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