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Coagulation Studies

PT/INR, aPTT, fibrinogen, and D-dimer for bleeding and clotting. 7 tests, 4 with a taught threshold.

Coagulation Studies: conventional and SI reference ranges and taught thresholds for 7 tests
TestConventionalSIThreshold
Activated Partial Thromboplastin Time (aPTT)25-35 seconds25-35 seconds> 70 seconds (bleeding risk)
Bleeding Time2-7 minutes2-7 minutes-
D-Dimer< 0.5 (negative) µg/mL FEU< 0.5 mg/L FEU-
Fibrinogen200-400 mg/dL2-4 g/L< 100 mg/dL (bleeding risk)
International Normalized Ratio (INR)0.8-1.1 (off anticoagulation) ratio0.8-1.1 ratio> 5.0 (high spontaneous bleeding risk)
Prothrombin Time (PT)11-13.5 seconds11-13.5 seconds> 30 seconds (marked bleeding risk)
Thrombin Time14-19 seconds14-19 seconds-

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Frequently asked questions

What tests are in a Coagulation Studies?

The Coagulation Studies on this page lists 7 tests: Activated Partial Thromboplastin Time (aPTT), Bleeding Time, D-Dimer, Fibrinogen, International Normalized Ratio (INR), Prothrombin Time (PT), Thrombin Time. Each is shown with its conventional and SI teaching reference range.

What does the Coagulation Studies check for?

PT/INR, aPTT, fibrinogen, and D-dimer for bleeding and clotting. These are educational teaching values - ranges vary by laboratory and method, and are not for clinical decisions.

Which Coagulation Studies values are critical?

4 of the 7 tests in this Coagulation Studies carry a taught threshold: Activated Partial Thromboplastin Time (aPTT) (> 70 seconds (bleeding risk)); Fibrinogen (< 100 mg/dL (bleeding risk)); International Normalized Ratio (INR) (> 5.0 (high spontaneous bleeding risk)); Prothrombin Time (PT) (> 30 seconds (marked bleeding risk)). These are teaching thresholds, not clinical cutoffs - always use the values your laboratory reports.